Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2023884 | 1.00 | ELANE (0.45) | ELANEHPGDFABP7FABP5F2 | |
| SCHEMBL6024185 | 1.00 | ELANE (0.45) | ELANEHPGDFABP7FABP5F2 | |
| SCHEMBL26679383 | 0.83 | GAA (0.50) | ELANEHPGDFABP7FABP5F2 | |
| SCHEMBL8466630 | 0.81 | ELANE (0.49) | ELANEHPGDFABP7FABP5CASP1 | |
| SCHEMBL7484716 | 0.81 | FABP7 (0.46) | ELANEHPGDFABP7FABP5CASP1 | |
| SCHEMBL6250804 | 0.81 | FABP7 (0.46) | ELANEHPGDFABP7FABP5CASP1 | |
| SCHEMBL14618064 | 0.81 | ALDH1A1 (0.50) | ELANEHPGDFABP7FABP5F2 | |
| SCHEMBL18562169 | 0.81 | ALDH1A1 (0.50) | ELANEHPGDFABP7FABP5F2 | |
| SCHEMBL31711177 | 0.77 | F2 (0.45) | ELANEHPGDFABP7FABP5F2 | |
| SCHEMBL8799263 | 0.76 | TSHR (0.44) | FABP7FABP5CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685119-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005049594-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |