SCHEMBL6025231

SCHEMBL6025231

CCCCCCOC(=O)/C(=N/OS(=O)(=O)c1ccc(C)cc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.40
RECQL P46063 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
S1PR3 Q99500 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HPGD P15428 1/20 0.38
PLA2G2C Q5R387 1/20 0.38
POLB P06746 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CTSL P07711 1/20 0.38
MEN1 O00255 1/20 0.38
APAF1 O14727 1/20 0.38
USP2 O75604 1/20 0.38
HSP90AA1 P07900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6024753 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRRECQLSMN1; SMN2
SCHEMBL6025268 0.96 POLB (0.41) ALDH1A1TSHRRECQLSMN1; SMN2TP53
SCHEMBL6025274 0.96 POLB (0.41) ALDH1A1TSHRRECQLSMN1; SMN2TP53
SCHEMBL6024497 0.91 LMNA (0.43) ALDH1A1LMNARECQLSMN1; SMN2TP53
SCHEMBL6024500 0.91 LMNA (0.43) ALDH1A1LMNARECQLSMN1; SMN2TP53
SCHEMBL6025465 0.90 GAA (0.43) ALDH1A1LMNATSHRSMN1; SMN2CYP3A4
SCHEMBL6025463 0.90 GAA (0.43) ALDH1A1LMNATSHRSMN1; SMN2CYP3A4
SCHEMBL6025593 0.85 ALDH1A1 (0.41) ALDH1A1LMNARECQLSMN1; SMN2TP53
SCHEMBL6025595 0.85 ALDH1A1 (0.41) ALDH1A1LMNARECQLSMN1; SMN2TP53
SCHEMBL6025349 0.85 GAA (0.45) ALDH1A1LMNATSHRRECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP claimed
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP disclosed
EP-1635220-A2 Oxime derivatives and the use thereof as photoinitiators Ciba Specialty Chemicals Holding Inc. (CH) 2006-03-15 EP disclosed
US-6806024-B1 MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-19 US disclosed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO disclosed