SCHEMBL6025239

SCHEMBL6025239

COCCOC(=O)C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
HPGD P15428 1/20 0.54
LMNA P02545 3/20 0.49
MAPT P10636 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HSP90AA1 P07900 1/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CA2 P00918 1/20 0.49
CES2 O00748 7/20 0.47
CES1 P23141 7/20 0.47
TDP1 Q9NUW8 2/20 0.44
POLB P06746 2/20 0.44
AKT1 P31749 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4738627 0.90 CES2 (0.56) HPGDLMNAMAPTKDM4EKMT2A
SCHEMBL665971 0.85 CES2 (0.50) HPGDLMNAMAPTKDM4EKMT2A
SCHEMBL13982035 0.85 CES2 (0.50) HPGDLMNAMAPTKDM4EKMT2A
SCHEMBL30478610 0.85 CES2 (0.50) HPGDLMNAMAPTKDM4EKMT2A
SCHEMBL3312136 0.85 CES2 (0.50) HPGDLMNAMAPTKDM4EKMT2A
Benzil SCHEMBL29078914 0.84 HPGD (0.57) TSHRHPGDLMNAMAPTKDM4E
SCHEMBL14006388 0.84 CES2 (0.66) HPGDLMNAMAPTKMT2AALDH1A1
SCHEMBL1119144 0.83 LMNA (0.67) TSHRLMNAMAPTKMT2AALDH1A1
SCHEMBL16044823 0.83 TDP1 (0.66) TSHRLMNAKDM4EKMT2AALDH1A1
SCHEMBL14547812 0.82 TDP1 (0.59) LMNAMAPTKDM4EALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020015966-A1 PHOTO-CURABLE RESIN COMPOSITION FOR 3D PRINTING CLARIANT INTERNATIONAL LTD (CH) 2020-01-23 WO disclosed
WO-2020015964-A1 PHOTO-CURABLE RESIN COMPOSITION FOR 3D PRINTING CLARIANT INTERNATIONAL LTD (CH) 2020-01-23 WO disclosed
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP disclosed
EP-1635220-A2 Oxime derivatives and the use thereof as photoinitiators Ciba Specialty Chemicals Holding Inc. (CH) 2006-03-15 EP disclosed
US-6806024-B1 MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-19 US disclosed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO disclosed