SCHEMBL6025244

SCHEMBL6025244

Cc1ccc(/C(=N\OS(=O)(=O)c2ccc(C)cc2)C(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
GAA P10253 2/20 0.42
GFER P55789 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 2/20 0.41
AKR1C3 P42330 1/20 0.41
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41
XBP1 P17861 1/20 0.41
MAPK1 P28482 1/20 0.41
MPI P34949 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6025245 1.00 STAT3 (0.44) STAT3KMT2AMEN1GAAGFER
SCHEMBL6024583 0.94 RECQL (0.47) KMT2AMEN1TDP1MAPTALDH1A1
SCHEMBL6024585 0.94 RECQL (0.47) KMT2AMEN1TDP1MAPTALDH1A1
SCHEMBL6025440 0.93 KMT2A (0.49) STAT3KMT2AMEN1GAATDP1
SCHEMBL6025438 0.93 KMT2A (0.49) STAT3KMT2AMEN1GAATDP1
SCHEMBL6025374 0.92 ALDH1A1 (0.50) KMT2AMEN1GAAGFERTDP1
SCHEMBL6025371 0.92 ALDH1A1 (0.50) KMT2AMEN1GAAGFERTDP1
SCHEMBL6025673 0.91 PPARG (0.45) STAT3KMT2AMEN1GAAGFER
SCHEMBL6025057 0.91 KMT2A (0.45) STAT3KMT2AMEN1GAATDP1
SCHEMBL6024807 0.91 ALDH1A1 (0.45) STAT3KMT2AMEN1GAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP claimed