Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025371 | 1.00 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTTP53LMNA | |
| SCHEMBL6025244 | 0.92 | STAT3 (0.44) | ALDH1A1GAAMAPTLMNACYP2C9 | |
| SCHEMBL6025245 | 0.92 | STAT3 (0.44) | ALDH1A1GAAMAPTLMNACYP2C9 | |
| SCHEMBL6024585 | 0.86 | RECQL (0.47) | ALDH1A1MAPTTP53LMNAKMT2A | |
| SCHEMBL6024583 | 0.86 | RECQL (0.47) | ALDH1A1MAPTTP53LMNAKMT2A | |
| SCHEMBL6025438 | 0.85 | KMT2A (0.49) | ALDH1A1GAAMAPTTP53LMNA | |
| SCHEMBL6025440 | 0.85 | KMT2A (0.49) | ALDH1A1GAAMAPTTP53LMNA | |
| SCHEMBL6024701 | 0.85 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTTP53LMNA | |
| SCHEMBL6024704 | 0.85 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTTP53LMNA | |
| SCHEMBL6024508 | 0.84 | PAX8 (0.52) | ALDH1A1GAAMAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163553-B1 | OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | claimed |