SCHEMBL6025411

SCHEMBL6025411

C=CCSC1=C(SCC=C)SC(=C2SC(SCC=C)=C(SCC=C)S2)S1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.36
▸ HPGD P15428 3/20 0.36
▸ TRPA1 O75762 2/20 0.36
▸ CYP3A4 P08684 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ ALOX5 P09917 1/20 0.36
▸ LMNA P02545 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7248147 0.67 ALDH1A1 (0.47) ALDH1A1HPGDTRPA1CYP3A4SMN1; SMN2
SCHEMBL2358144 0.67 MAPT (0.46) ALDH1A1HPGDCYP3A4SMN1; SMN2TSHR
SCHEMBL13468208 0.66 SMN1; SMN2 (0.38) ALDH1A1HPGDCYP3A4SMN1; SMN2ALOX15
SCHEMBL8521655 0.61 ALDH1A1 (0.40) ALDH1A1HPGDTRPA1CYP3A4SMN1; SMN2
SCHEMBL8770615 0.61 ALDH1A1 (0.40) ALDH1A1HPGDTRPA1CYP3A4SMN1; SMN2
SCHEMBL25435056 0.61 — —
SCHEMBL8755108 0.61 L3MBTL1 (0.41) ALDH1A1HPGDTRPA1CYP3A4SMN1; SMN2
SCHEMBL13085024 0.61 NPSR1 (0.46) ALDH1A1HPGDTRPA1CYP3A4SMN1; SMN2
SCHEMBL176389 0.59 ALDH1A1 (0.43) ALDH1A1HPGDTRPA1CYP3A4SMN1; SMN2
SCHEMBL1459442 0.58 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1488277-A4 SWITCHABLE ELECTRO-OPTICAL LAMINATES AVERY DENNISON CORP (US) 2006-08-16 — — EP disclosed
US-7023600-B2 Switchable electro-optical laminates AVERY DENNISON CORPORATION (US) 2006-04-04 — — US disclosed
US-6963435-B2 Switchable electro-optical laminates AVERY DENNISON CORPORATION (US) 2005-11-08 — — US disclosed
US-20050083564-A1 Switchable electro-optical laminates MALLYA PRAKASH (US) 2005-04-21 — — US disclosed
EP-1488277-A2 SWITCHABLE ELECTRO-OPTICAL LAMINATES AVERY DENNISON CORPORATION (US) 2004-12-22 — — EP disclosed
US-20030193709-A1 Switchable electro-optical laminates AVERY DENNISON CORPORATION 2003-10-16 — — US disclosed
WO-2003083523-A2 SWITCHABLE ELECTRO-OPTICAL LAMINATES AVERY DENNISON CORPORATION (US) 2003-10-09 — — WO disclosed
US-6219019-B1 Liquid crystal display apparatus and method for driving the same KABUSHIKI KAISHA TOSHIBA (JP) 2001-04-17 — — US disclosed
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