Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360004 | 0.84 | METAP2 (0.46) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL27174135 | 0.84 | METAP2 (0.46) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL30011414 | 0.84 | METAP2 (0.46) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL51294 | 0.84 | METAP2 (0.46) | MAOACES1BCHEALDH1A1CYP1A2 | |
| SCHEMBL6385750 | 0.84 | CES1 (0.59) | MAOACES1GAACYP19A1MAPK14 | |
| SCHEMBL10258112 | 0.78 | METAP2 (0.41) | MAOACES1BCHECYP1A2CYP2C19 | |
| SCHEMBL30701140 | 0.78 | MAOA (0.61) | MAOACES1BCHEGAACYP19A1 | |
| Anthrone SCHEMBL27274516 | 0.77 | MAOA (0.60) | MAOACES1BCHEGAACYP19A1 | |
| Anthrone SCHEMBL18143 | 0.77 | MAOA (1.00) | MAOACES1BCHECYP19A1TNF | |
| Anthrone SCHEMBL29357010 | 0.77 | MAOA (1.00) | MAOACES1BCHECYP19A1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017997-A1 | SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY | DIAZANS LIMITED (CA) | 2001-03-15 | — | — | WO | claimed |
| US-9905886-B2 | Non-aqueous liquid electrolyte for secondary battery and secondary battery | FUJIFILM CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-9905886-B2 | Non-aqueous liquid electrolyte for secondary battery and secondary battery | FUJIFILM CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-20140377666-A1 | NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY | FUJIFILM CORPORATION (JP) | 2014-12-25 | — | — | US | disclosed |
| US-20140377666-A1 | NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY | FUJIFILM CORPORATION (JP) | 2014-12-25 | — | — | US | disclosed |
| EP-1723116-A2 | TETRAHYDROQUINOLINONES AND THEIR USE AS ANTAGONISTS OF METABOTROPIC GLUTAMATE RECEPTORS | Merz Pharma GmbH & Co. KGaA (DE) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005082856-A2 | TETRAHYDROQUINOLINONES AND THEIR USE AS ANTAGONISTS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2005-09-09 | — | — | WO | disclosed |
| WO-2001017997-A1 | SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY | DIAZANS LIMITED (CA) | 2001-03-15 | — | — | WO | disclosed |