Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025936 | 1.00 | AKR1C3 (0.44) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6025455 | 0.85 | ALDH1A1 (0.46) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6025109 | 0.85 | ALDH1A1 (0.46) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6024796 | 0.82 | GAA (0.39) | ALDH1A1TSHRSMN1; SMN2MAPTGAA | |
| SCHEMBL6024791 | 0.82 | GAA (0.39) | ALDH1A1TSHRSMN1; SMN2MAPTGAA | |
| SCHEMBL6024807 | 0.81 | ALDH1A1 (0.45) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6024809 | 0.81 | ALDH1A1 (0.45) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6025256 | 0.79 | ALDH1A1 (0.41) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6025254 | 0.79 | ALDH1A1 (0.41) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7786859 | 0.76 | MAPT (0.41) | AKR1C3HAO1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163553-B1 | OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | claimed |