Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024791 | 1.00 | GAA (0.39) | GAACYP2C19TSHRPOLBPTGS2 | |
| SCHEMBL12629321 | 0.88 | CES2 (0.43) | GAACYP2C19TSHRPOLBLMNA | |
| SCHEMBL26325460 | 0.88 | CES2 (0.42) | GAACYP2C19TSHRPOLBPTGS2 | |
| SCHEMBL6024818 | 0.85 | TSHR (0.43) | GAACYP2C19TSHRPOLBMAPT | |
| SCHEMBL26325442 | 0.85 | TSHR (0.43) | GAACYP2C19TSHRPOLBMAPT | |
| SCHEMBL6025557 | 0.85 | TSHR (0.43) | GAACYP2C19TSHRPOLBMAPT | |
| SCHEMBL6025935 | 0.82 | AKR1C3 (0.44) | GAATSHRAKR1C2AKR1C1LMNA | |
| SCHEMBL6025936 | 0.82 | AKR1C3 (0.44) | GAATSHRAKR1C2AKR1C1LMNA | |
| SCHEMBL6025570 | 0.80 | ALDH1A1 (0.42) | POLBLMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL26325437 | 0.79 | GAA (0.44) | GAATSHRPOLBPTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163553-B1 | OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | claimed |