Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026134 | 0.80 | MEN1 (0.50) | MAPTGAACYP1A2CYP3A4MEN1 | |
| SCHEMBL4699425 | 0.80 | RXFP3 (0.42) | RXFP3MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL4699822 | 0.79 | MAPT (0.63) | RXFP3MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL4699467 | 0.73 | RXFP3 (0.45) | RXFP3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL4698350 | 0.73 | MAPT (0.67) | RXFP3MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL4701255 | 0.73 | RXFP3 (0.84) | RXFP3MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL4700992 | 0.70 | RXFP3 (0.66) | RXFP3MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL7623120 | 0.70 | MAPT (0.74) | MAPTGAACYP1A2CYP3A4MEN1 | |
| SCHEMBL4332218 | 0.70 | MAPT (1.00) | MAPTGAACYP1A2CYP3A4MEN1 | |
| SCHEMBL7623116 | 0.70 | MAPT (0.74) | MAPTGAACYP1A2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |