Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699467 | 0.88 | RXFP3 (0.45) | RXFP3MAPTALDH1A1ADORA2AKDM4E | |
| SCHEMBL6025034 | 0.81 | NPC1 (0.43) | MAPTALDH1A1GAAKDM4EFAAH | |
| SCHEMBL6026142 | 0.80 | RXFP3 (0.53) | RXFP3MAPTALDH1A1GAAKDM4E | |
| SCHEMBL4699822 | 0.79 | MAPT (0.63) | RXFP3MAPTALDH1A1GAAKDM4E | |
| SCHEMBL4700168 | 0.72 | ADORA2A (0.47) | RXFP3MAPTALDH1A1GAAADORA2A | |
| SCHEMBL6026475 | 0.70 | GPR84 (0.39) | MAPTALDH1A1GAAKDM4ECYP1A2 | |
| SCHEMBL6026134 | 0.67 | MEN1 (0.50) | MAPTALDH1A1GAAKDM4ECYP1A2 | |
| SCHEMBL4700992 | 0.66 | RXFP3 (0.66) | RXFP3MAPTALDH1A1GAAADORA2A | |
| SCHEMBL22193942 | 0.65 | MEN1 (0.56) | MAPTALDH1A1GAAKDM4ECYP1A2 | |
| SCHEMBL4697805 | 0.65 | ADORA2A (0.60) | RXFP3MAPTALDH1A1GAAADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |