Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR1D | P28221 | 4/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | MC3R | P41968 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699425 | 0.88 | RXFP3 (0.42) | RXFP3ADORA2ARAB9AFAAHMEN1 | |
| SCHEMBL4700992 | 0.81 | RXFP3 (0.66) | RXFP3ADORA2ARAB9AHTR1AHTR2C | |
| SCHEMBL4699037 | 0.78 | ADORA2A (0.51) | RXFP3ADORA2ARAB9AHTR1AHTR2C | |
| SCHEMBL6025034 | 0.78 | NPC1 (0.43) | RAB9AFAAHMEN1KMT2AMAPT | |
| SCHEMBL6026142 | 0.73 | RXFP3 (0.53) | RXFP3RAB9APTGS2MEN1KMT2A | |
| SCHEMBL4697805 | 0.70 | ADORA2A (0.60) | RXFP3ADORA2ARAB9AHTR1AHTR2C | |
| SCHEMBL4700168 | 0.69 | ADORA2A (0.47) | RXFP3ADORA2ARAB9AHTR1AHTR2C | |
| SCHEMBL4700117 | 0.67 | HTR1A (0.53) | RXFP3ADORA2ARAB9AHTR1AHTR2C | |
| SCHEMBL6026475 | 0.67 | GPR84 (0.39) | RAB9AMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL4699822 | 0.67 | MAPT (0.63) | RXFP3RAB9APTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |