Sugi Predict

Sugi Predict / Compounds / Biphenyl

Biphenyl

Biphenyl

SCHEMBL6026340

O=C(O)C(OO)C(O)CO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.40
▸ SRR Q9GZT4 2/20 0.39
▸ PSAT1 Q9Y617 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ GAA P10253 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ PPARG P37231 8/20 0.38
▸ PPARA Q07869 6/20 0.38
▸ PTGS2 P35354 1/20 0.38
▸ SLC1A5 Q15758 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ SLC1A3 P43003 2/20 0.37
▸ SLC1A2 P43004 2/20 0.37
▸ SLC1A1 P43005 2/20 0.37
▸ CYP2D6 P10635 2/20 0.37
▸ MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL612464 0.84 PDE4A (0.44) TSHRCYP2C9SLC1A3SLC1A2SLC1A1
SCHEMBL7079117 0.76 PPARG (0.46) CYP1A2CYP2C9CYP2C19GAAPKM
Biphenyl SCHEMBL7197525 0.76 ALDH1A1 (0.50) KMT2ATSHRCYP1A2GAAALDH1A1
Niacin SCHEMBL810524 0.75 ALDH1A1 (0.57) KMT2ACYP2C9CYP2C19GAAALDH1A1
SCHEMBL6026529 0.74 LMNA (0.50) CYP1A2PPARGPPARA
SCHEMBL29991463 0.74 TSHR (0.70) KMT2ATP53TSHRCYP1A2ALDH1A1
Niacinamide SCHEMBL810723 0.74 F7 (0.58) KMT2AGAAALDH1A1MEN1
SCHEMBL7603543 0.71 SLC1A1 (0.47) KMT2ASRRTP53TSHRCYP1A2
SCHEMBL7565757 0.71 TSHR (0.51) KMT2ATP53TSHRALDH1A1CYP2D6
SCHEMBL10753257 0.71 PDE4A (0.56) TSHRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7019029-B2 Skin whiteners containing hydroxytetronic acid derivatives THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT 2006-03-28 — — US disclosed
US-7019029-B2 Skin whiteners containing hydroxytetronic acid derivatives THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT 2006-03-28 — — US disclosed
US-20020141956-A1 Skin whiteners containing hydroxytetronic acid derivatives THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT 2002-10-03 — — US disclosed
US-20020141956-A1 Skin whiteners containing hydroxytetronic acid derivatives THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT 2002-10-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020141956-A1 Skin whiteners containing hydroxytetronic acid derivatives TYR, PPP6C, CYP26A1 KMT2A 2742/4885SRR 793/4885PSAT1 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.