Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026628 | 0.85 | MEN1 (0.37) | MCL1NOTUMLMNAHTTMGAT2 | |
| SCHEMBL6932927 | 0.83 | CHRNA1 (0.42) | MCL1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7983353 | 0.83 | CHRNA1 (0.42) | MCL1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7984718 | 0.83 | CHRNA1 (0.42) | MCL1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7956291 | 0.82 | PTGER3 (0.40) | MCL1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL7969034 | 0.81 | ALDH1A1 (0.38) | NOTUMSMN1; SMN2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL6934036 | 0.81 | PTGS2 (0.37) | MAPTLMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL7966664 | 0.81 | HCAR2 (0.46) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL7030070 | 0.81 | HCAR2 (0.46) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL7965515 | 0.81 | PTGS2 (0.37) | MAPTLMNASMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019029-B2 | Skin whiteners containing hydroxytetronic acid derivatives | THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT | 2006-03-28 | — | — | US | disclosed |
| US-20020141956-A1 | Skin whiteners containing hydroxytetronic acid derivatives | THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY, AS ADMINISTRATIVE AGENT | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020141956-A1 | Skin whiteners containing hydroxytetronic acid derivatives | TYR, PPP6C, CYP26A1 | MCL1 4292/4885MAPT 1510/4885NOTUM 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.