Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 7/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026449 | 0.90 | BMP1 (0.44) | BMP1MMP12OPRM1OPRD1OPRK1 | |
| SCHEMBL6025330 | 0.88 | BMP1 (0.43) | BMP1MMP12OPRM1OPRD1OPRK1 | |
| SCHEMBL6024785 | 0.87 | BMP1 (0.42) | BMP1MMP12OPRM1OPRD1OPRK1 | |
| SCHEMBL6024825 | 0.84 | MAPT (0.40) | OPRM1OPRD1OPRK1MAPTMEN1 | |
| Formaldehyde SCHEMBL6024828 | 0.83 | MAPT (0.40) | OPRM1OPRD1OPRK1MAPTMEN1 | |
| SCHEMBL6023890 | 0.82 | BMP1 (0.44) | BMP1MMP12MAPTALDH1A1GAA | |
| SCHEMBL6024553 | 0.80 | TAS1R3 (0.52) | BMP1MMP12 | |
| SCHEMBL17685459 | 0.78 | BMP1 (0.47) | BMP1MMP12 | |
| SCHEMBL6024347 | 0.77 | BMP1 (0.49) | BMP1MMP12HPGD | |
| SCHEMBL6023887 | 0.77 | BMP1 (0.47) | BMP1MMP12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019003-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-28 | — | — | US | claimed |
| US-7019003-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-28 | — | — | US | disclosed |