SCHEMBL6026792

SCHEMBL6026792

[c]1nc2ccccc2cc1-c1ccccc1SCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
RAB9A P51151 4/20 0.38
NPC1 O15118 3/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
ELANE P08246 2/20 0.35
MAOB P27338 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
HTT P42858 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
DRD2 P14416 1/20 0.34
TBXA2R P21731 1/20 0.34
LMNA P02545 3/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1236891 0.78 POLB (0.42) POLBRAB9ANPC1SMN1; SMN2ELANE
SCHEMBL29037875 0.74 POLB (0.47) POLBRAB9ANPC1SMN1; SMN2ELANE
SCHEMBL2187375 0.70 KMT2A (0.42) POLBRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL628270 0.69 ALDH1A1 (0.43) POLBRAB9ANPC1ALDH1A1TDP1
SCHEMBL2476662 0.69 POLB (0.49) POLBRAB9ANPC1SMN1; SMN2MAOB
SCHEMBL28101142 0.68 POLB (0.47) POLBRAB9ANPC1SMN1; SMN2ELANE
SCHEMBL4722008 0.68 ALDH1A1 (0.39) POLBRAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL28101141 0.67 POLB (0.50) POLBSMN1; SMN2ELANEMAOBHTT
SCHEMBL6777717 0.67 POLB (0.59) POLBRAB9ANPC1SMN1; SMN2TDP1
SCHEMBL577790 0.67 ALDH1A1 (0.51) RAB9ASMN1; SMN2ALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110268037-B Organic electroluminescent device 罗门哈斯电子材料韩国有限公司 2023-09-29 CN disclosed
EP-1648880-A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN Euro-Celtique S.A. (LU) 2006-04-26 EP disclosed
WO-2005012287-A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 2005-02-10 WO disclosed
US-6340599-B1 TERBIUM, DYSPROSIUM, SAMARIUM, OSMIUM, OR RUTHENIUM COMPLEX WITH UNSATURATED OXYARYL COMPOUND DADE BEHRING MARBURG GMBH (DE) 2002-01-22 US disclosed