Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722008 | 0.87 | ALDH1A1 (0.39) | KMT2AMEN1GSK3BCDK5CDK5R1 | |
| SCHEMBL9032374 | 0.82 | CYP1A2 (0.49) | ALDH1A1HPGDMAPTHSD17B10ESR1 | |
| SCHEMBL7499231 | 0.79 | BCHE (0.46) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL2447211 | 0.78 | KDM4E (0.44) | KMT2AMEN1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL6770764 | 0.76 | KMT2A (0.37) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL577790 | 0.76 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL3933846 | 0.76 | KDM4E (0.41) | KMT2AALDH1A1HPGDMAPTGLA | |
| SCHEMBL21630330 | 0.75 | MEN1 (0.41) | KMT2AMEN1GSK3BCDK5CDK5R1 | |
| SCHEMBL4875674 | 0.74 | MAPT (0.39) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL628270 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903037-A1 | 1-(hetero)aryl-3-[heteroaryl-piperidin-4yl]-thiourea derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-03-26 | — | — | EP | claimed |
| US-20050042676-A1 | Characterising polypeptides | ELECTROPHORETICS LIMITED (GB) | 2005-02-24 | — | — | US | claimed |
| US-20050042713-A1 | Characterising polypeptides | PROTEOME SCIENCES R&D GMBH & CO. KG (DE) | 2005-02-24 | — | — | US | claimed |
| EP-1397684-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & Co. KG (DE) | 2004-03-17 | — | — | EP | claimed |
| EP-1397505-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & CO.KG (DE) | 2004-03-17 | — | — | EP | claimed |
| EP-1267170-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-18 | — | — | EP | claimed |
| WO-2002099436-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | claimed |
| WO-2002099124-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | claimed |
| EP-1265072-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-11 | — | — | EP | claimed |
| US-6117874-A | AROMATIC RING-SUBSTITUTED 4-HYDROXYTETRAHYDROQUINOLINES | PFIZER INC. (US) | 2000-09-12 | — | — | US | claimed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | claimed |
| CN-106232592-A | Triazine compound and method for producing same | 东曹株式会社 | 2016-12-14 | — | — | CN | disclosed |
| EP-2968322-A2 | MAP KINASE MODULATORS AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 2016-01-20 | — | — | EP | disclosed |
| US-9145481-B2 | Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation | WATERS TECHNOLOGIES CORPORATION (US) | 2015-09-29 | — | — | US | disclosed |
| EP-2343285-B1 | Peptoid compounds useful as antibiotics | UNIV WOLLONGONG (AU) | 2015-02-25 | — | — | EP | disclosed |
| US-20050043509-A1 | Peptoid compounds | UNIVERSITY OF WOLLONGONG | 2005-02-24 | — | — | US | disclosed |
| EP-1412336-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003002545-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2003-01-09 | — | — | WO | disclosed |
| US-4782052-A | ANTIULCER | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1988-11-01 | — | — | US | disclosed |
| EP-0177361-A2 | Octahydroindolo-[2,3-a]quinolizin-l-yl-alkanecarboxylic acid amides and salts thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050042713-A1 | Characterising polypeptides | PTMS, ANPEP, DNPEP | KMT2A 3531/4885MEN1 2310/4885GSK3B 4617/4885 |
| US-20050043509-A1 | Peptoid compounds | VIP, FPR1, VIPR1 | KMT2A 4739/4885MEN1 3065/4885GSK3B 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.