SCHEMBL6026964

SCHEMBL6026964

CCCC[Si](C)(C)[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14261163 0.72 TSHR (0.33) TSHRLMNA
SCHEMBL16602995 0.72 TSHR (0.33) TSHRLMNA
SCHEMBL6185373 0.71 TSHR (0.38) TSHRTDP1LMNA
SCHEMBL4644804 0.70 TSHR (0.32) TSHRTDP1LMNA
SCHEMBL2269105 0.70 TSHR (0.33) TSHRTDP1LMNA
SCHEMBL2102289 0.70 TSHR (0.32) TSHRTDP1LMNA
SCHEMBL1981869 0.69 TSHR (0.50) TSHRLMNA
SCHEMBL18108485 0.69
SCHEMBL17735524 0.69 TSHR (0.35) TSHRLMNA
SCHEMBL15914659 0.69 TSHR (0.35) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1701930-A1 PROCESS FOR THE PREPARATION OF ALIPHATIC PRIMARY ALCOHOLS AND RELATED INTERMEDIATES IN SUCH PROCESS DSM IP Assets B.V. (NL) 2006-09-20 EP disclosed
WO-2005047223-A1 PROCESS FOR THE PREPARATION OF ALIPHATIC PRIMARY ALCOHOLS AND RELATED INTERMEDIATES IN SUCH PROCESS DSM IP ASSETS B.V. (NL) 2005-05-26 WO disclosed