SCHEMBL6027169

SCHEMBL6027169

CCCCC/C=C\C/C=C\CCCCCCCC(=O)O[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)C(O)C(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.58
NR5A2 O00482 1/20 0.58
NR5A1 Q13285 1/20 0.58
S1PR1 P21453 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
RECQL P46063 1/20 0.54
MAPT P10636 1/20 0.54
SMPD1 P17405 1/20 0.49
PLA2G1B P04054 1/20 0.48
PLA2G2A P14555 1/20 0.48
ADRA1D P25100 1/20 0.48
PTAFR P25105 1/20 0.48
HTR1D P28221 1/20 0.48
HTR2C P28335 1/20 0.48
ADRA1B P35368 1/20 0.48
DRD3 P35462 1/20 0.48
TMEM97 Q5BJF2 1/20 0.48
PLA2G10 O15496 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3861371 0.97 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL3867322 0.97 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL17065552 0.92 SMN1; SMN2 (0.67) ALDH1A1SMN1; SMN2NR5A2NR5A1MEN1
SCHEMBL825278 0.92 SMN1; SMN2 (0.67) ALDH1A1SMN1; SMN2NR5A2NR5A1MEN1
SCHEMBL6912576 0.90 SMN1; SMN2 (0.61) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL10693602 0.88 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
Phosphocholine SCHEMBL5087547 0.87 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
Phosphocholine SCHEMBL6534600 0.86 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL15689715 0.84 ALDH1A1 (0.81) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL3410263 0.84 ALDH1A1 (0.81) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1628634-A1 NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS CHIESI FARMACEUTICI S.p.A. (IT) 2006-03-01 EP disclosed
WO-2004105726-A1 NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS CHIESI FARMACEUTICI S.P.A. (IT) 2004-12-09 WO disclosed