Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.52 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710185 | 0.91 | SMN1; SMN2 (0.61) | MEN1KMT2ASMN1; SMN2PLA2G1BPLA2G2A | |
| SCHEMBL17962981 | 0.91 | SMN1; SMN2 (0.61) | MEN1KMT2ASMN1; SMN2PLA2G1BPLA2G2A | |
| SCHEMBL18210636 | 0.91 | SMN1; SMN2 (0.61) | MEN1KMT2ASMN1; SMN2PLA2G1BPLA2G2A | |
| SCHEMBL6027169 | 0.88 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AS1PR1SMN1; SMN2 | |
| SCHEMBL3867322 | 0.85 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AS1PR1SMN1; SMN2 | |
| SCHEMBL3861371 | 0.85 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AS1PR1SMN1; SMN2 | |
| SCHEMBL29360640 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AS1PR1SMN1; SMN2 | |
| SCHEMBL31596828 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AS1PR1SMN1; SMN2 | |
| SCHEMBL29748725 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AS1PR1SMN1; SMN2 | |
| SCHEMBL29638871 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AS1PR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746652-A | Method of inducing diuresis with lysophospholipids | WAKE FOREST UNIVERSITY (US) | 1988-05-24 | — | — | US | disclosed |