SCHEMBL6027272

SCHEMBL6027272

CCOCC(OCC)(OCC)OC(=O)c1ccccc1C(=O)OC(COCC)(OCC)OCC

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.49
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP3A4 P08684 3/20 0.39
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.37
CDC25B P30305 1/20 0.37
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
NPC1 O15118 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27367268 0.94 TSHR (0.44) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL17798226 0.90 TSHR (0.50) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL3667880 0.87 TSHR (0.53) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL22833246 0.86 CYP2D6 (0.46) TSHRALDH1A1TDP1L3MBTL1HSD17B10
SCHEMBL17797777 0.83 CA1 (0.41) TSHRALDH1A1TDP1CYP3A4MAPK1
SCHEMBL17798309 0.83 ALDH1A1 (0.57) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL17798283 0.81 ALDH1A1 (0.41) TSHRALDH1A1KDM4ENPC1
SCHEMBL27504444 0.80 TSHR (0.46) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL206691 0.79 TSHR (0.54) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL16278306 0.78 LMNA (0.43) TSHRALDH1A1TDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230376-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES Solutia Inc. (US) 2017-10-18 EP claimed
WO-2016094203-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTIA INC. (US) 2016-06-16 WO claimed
US-5466535-A Polyester material on surface with crosslinked adherent layer of acrylic resin and phthalate ester IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 US claimed
EP-0358181-A2 Polyvinyl chloride blends having improved physical properties The Geon Company (US) 1990-03-14 EP claimed
EP-3230376-B1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTIA INC (US) 2025-09-24 EP disclosed
US-11358376-B2 Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties SOLUTIA INC. (US) 2022-06-14 US disclosed
US-10563057-B2 Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties SOLUTIA INC. (US) 2020-02-18 US disclosed
US-20190202179-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTIA INC. (US) 2019-07-04 US disclosed
US-9963583-B2 Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties SOLUTIA INC. (US) 2018-05-08 US disclosed
EP-3230376-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES Solutia Inc. (US) 2017-10-18 EP disclosed
WO-2016094203-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTIA INC. (US) 2016-06-16 WO disclosed
US-20160160030-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTIA INC. (US) 2016-06-09 US disclosed
EP-0726847-B1 POLYMERIC FILM ICI PLC (GB) 1998-08-19 EP disclosed
EP-0576169-B1 Polymeric film ICI PLC (GB) 1997-03-12 EP disclosed
EP-0726847-A1 POLYMERIC FILM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-08-21 EP disclosed
US-5466535-A Polyester material on surface with crosslinked adherent layer of acrylic resin and phthalate ester IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 US disclosed
WO-1995012489-A1 POLYMERIC FILM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-05-11 WO disclosed
EP-0576169-A2 Polymeric film IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-29 EP disclosed
EP-0358181-A2 Polyvinyl chloride blends having improved physical properties The Geon Company (US) 1990-03-14 EP disclosed
US-3974080-A PHOSPHORIC ACID ESTER UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed