Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026607 | 1.00 | GSK3B (0.39) | GSK3BSCN3ASCN9APTPN1PTPN2 | |
| SCHEMBL6027187 | 0.90 | PTPN1 (0.48) | SCN3ASCN9APTPN1PTPN2NPC1 | |
| SCHEMBL6026686 | 0.90 | PTPN1 (0.48) | SCN3ASCN9APTPN1PTPN2NPC1 | |
| SCHEMBL6027147 | 0.85 | SCN3A (0.39) | SCN3ASCN9APTPN1PTPN2DHODH | |
| SCHEMBL6028319 | 0.84 | PTPN1 (0.54) | GSK3BSCN3ASCN9APTPN1PTPN2 | |
| SCHEMBL6029160 | 0.84 | PTPN1 (0.54) | GSK3BSCN3ASCN9APTPN1PTPN2 | |
| SCHEMBL6887918 | 0.82 | SCN2A (0.45) | — | |
| SCHEMBL6887915 | 0.82 | CNR2 (0.46) | NPC1RAB9AEPHX2 | |
| SCHEMBL6887689 | 0.80 | PTPN1 (0.44) | GSK3BSCN3ASCN9APTPN1PTPN2 | |
| SCHEMBL6885314 | 0.80 | NPC1 (0.53) | PTPN1PTPN2NPC1RAB9ANR2E3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613310-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | Avanir Pharmaceuticals (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091610-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | AVANIR PHARMACEUTICALS (US) | 2004-10-28 | — | — | WO | disclosed |