Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027187 | 0.87 | PTPN1 (0.48) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6026686 | 0.87 | PTPN1 (0.48) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6026607 | 0.85 | GSK3B (0.39) | SCN3ASCN9ARAB9ANPC1MAPT | |
| SCHEMBL6027331 | 0.85 | GSK3B (0.39) | SCN3ASCN9ARAB9ANPC1MAPT | |
| SCHEMBL6888068 | 0.84 | PTPN1 (0.51) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6031823 | 0.84 | PTPN1 (0.51) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6030700 | 0.84 | PTPN1 (0.51) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6029811 | 0.84 | PTPN1 (0.51) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6885880 | 0.82 | SCN3A (0.42) | SCN3ASCN9ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6887689 | 0.82 | PTPN1 (0.44) | SCN3ASCN9ARAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613310-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | Avanir Pharmaceuticals (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091610-A1 | IMIDAZOLE DERIVATIVES FOR TREATMENT OF ALLERGIC AND HYPERPROLIFERATIVE DISORDERS | AVANIR PHARMACEUTICALS (US) | 2004-10-28 | — | — | WO | disclosed |