Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029811 | 0.94 | PTPN1 (0.51) | PTPN1PTPN2SCN3ASCN9AGSK3B | |
| SCHEMBL6888068 | 0.94 | PTPN1 (0.51) | PTPN1PTPN2SCN3ASCN9AGSK3B | |
| SCHEMBL6030700 | 0.94 | PTPN1 (0.51) | PTPN1PTPN2SCN3ASCN9AGSK3B | |
| SCHEMBL6031823 | 0.94 | PTPN1 (0.51) | PTPN1PTPN2SCN3ASCN9AGSK3B | |
| SCHEMBL6028319 | 0.91 | PTPN1 (0.54) | PTPN1PTPN2SCN3ASCN9AGSK3B | |
| SCHEMBL6029160 | 0.91 | PTPN1 (0.54) | PTPN1PTPN2SCN3ASCN9AGSK3B | |
| SCHEMBL6884890 | 0.88 | PTPN1 (0.43) | PTPN1PTPN2SCN3ASCN9AGSK3B | |
| SCHEMBL6885880 | 0.86 | SCN3A (0.42) | PTPN1PTPN2SCN3ASCN9ARAB9A | |
| SCHEMBL14311202 | 0.84 | PTPN1 (0.62) | PTPN1PTPN2SCN3ASCN9ARAB9A | |
| SCHEMBL6028360 | 0.84 | PTPN1 (0.62) | PTPN1PTPN2SCN3ASCN9ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | AVANIR PHARMACEUTICALS | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | ICOS, TSLP, IKZF3 | PTPN1 2513/4885PTPN2 2100/4885SCN3A 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.