⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18421848 | 0.91 | SHBG (0.52) | — | |
| SCHEMBL13212040 | 0.91 | TP53 (0.32) | — | |
| SCHEMBL11892780 | 0.90 | TP53 (0.50) | — | |
| SCHEMBL11892781 | 0.90 | TP53 (0.50) | — | |
| SCHEMBL1665955 | 0.90 | TP53 (0.50) | — | |
| SCHEMBL12134648 | 0.90 | — | — | |
| SCHEMBL887649 | 0.87 | TP53 (0.54) | — | |
| SCHEMBL12134655 | 0.87 | TP53 (0.54) | — | |
| SCHEMBL18422051 | 0.87 | LMNA (0.34) | — | |
| SCHEMBL20240088 | 0.85 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612407-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist | BEONE MEDICINES I GMBH (CH) | 2026-04-28 | — | — | US | disclosed |
| CN-113423708-B | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2025-04-22 | — | — | CN | disclosed |
| EP-3921319-B1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE LTD (KY) | 2024-03-06 | — | — | EP | disclosed |
| US-20230167117-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEONE MEDICINES I GMBH (CH) | 2023-06-01 | — | — | US | disclosed |
| EP-3921319-A1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BeiGene, Ltd. (KY) | 2021-12-15 | — | — | EP | disclosed |
| CN-113423708-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-21 | — | — | CN | disclosed |
| WO-2020160710-A1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE, LTD. (KY) | 2020-08-13 | — | — | WO | disclosed |
| US-20170008890-A1 | SUBSTITUTED 4-AZAINDOLES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-01-12 | — | — | US | disclosed |
| EP-2766368-A1 | 5,7-SUBSTITUTED-IMIDAZO[1,2-C]PYRIMIDINES | Array Biopharma Inc. (US) | 2014-08-20 | — | — | EP | disclosed |
| US-20140228349-A1 | 5,7-SUBSTITUTED-IMIDAZO[1,2-C]PYRIMIDINES | ARRAY BIOPHARMA, INC. | 2014-08-14 | — | — | US | disclosed |
| US-8044092-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20100317872-A1 | THERAPEUTIC COMPOUNDS | ALLERGAN, INC. (US) | 2010-12-16 | — | — | US | disclosed |
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| US-7799821-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7674786-B2 | Therapeutic β-lactams | ALLERGAN, INC. (US) | 2010-03-09 | — | — | US | disclosed |
| WO-2009091764-A2 | THERAPEUTIC BETA-LACTAMS | ALLERGAN, INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| US-20090186866-A1 | THERAPEUTIC BETA-LACTAMS | ALLERGAN, INC. | 2009-07-23 | — | — | US | disclosed |
| US-20080113943-A1 | Therapeutic Beta-Lactams | ALLERGAN, INC. (US) | 2008-05-15 | — | — | US | disclosed |
| EP-0971904-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042682-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |