Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899810 | 0.84 | HPGDS (0.65) | HPGDSNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL6027479 | 0.83 | KMT2A (0.52) | SMN1; SMN2HPGDSNPC1RAB9AKMT2A | |
| SCHEMBL5702341 | 0.80 | RAB9A (0.62) | SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL126140 | 0.79 | HSD17B10 (0.54) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL27718121 | 0.78 | ELANE (0.53) | SMN1; SMN2HPGDSNPC1RAB9AKMT2A | |
| SCHEMBL15899801 | 0.78 | HPGD (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6027578 | 0.78 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AKMT2AGRM4 | |
| SCHEMBL15899850 | 0.77 | HPGDS (0.46) | SMN1; SMN2HPGDSNPC1RAB9AALDH1A1 | |
| SCHEMBL15899786 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AALDH1A1POLB | |
| SCHEMBL15899961 | 0.77 | GAA (0.47) | SMN1; SMN2HPGDSNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720829-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090292-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |