Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027549 | 1.00 | TSHR (0.40) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6024511 | 0.94 | TSHR (0.42) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6025552 | 0.90 | TSHR (0.42) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6025551 | 0.90 | TSHR (0.42) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6025498 | 0.78 | CA12 (0.53) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6025361 | 0.77 | MAPT (0.51) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14839188 | 0.77 | KMT2A (0.41) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6024507 | 0.76 | NPC1 (0.34) | MAPTKMT2AMEN1POLBRAB9A | |
| SCHEMBL6024672 | 0.75 | PAX8 (0.48) | TSHRMAPTCA1CA2CA7 | |
| SCHEMBL6024673 | 0.75 | PAX8 (0.48) | TSHRMAPTCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635220-A2 | Oxime derivatives and the use thereof as photoinitiators | Ciba Specialty Chemicals Holding Inc. (CH) | 2006-03-15 | — | — | EP | disclosed |