Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427178 | 0.85 | MEN1 (0.49) | ELANEALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL23458369 | 0.77 | ELANE (0.44) | ELANEHPGDMEN1CYP1A2KMT2A | |
| SCHEMBL29919660 | 0.77 | ELANE (0.44) | ELANEHPGDMEN1CYP1A2KMT2A | |
| SCHEMBL2714269 | 0.77 | KDM4E (0.53) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL29862254 | 0.75 | HTR1B (0.50) | ELANEALDH1A1KMT2A | |
| SCHEMBL30301305 | 0.75 | HTR1B (0.50) | ELANEALDH1A1KMT2A | |
| SCHEMBL1509321 | 0.75 | HTR1B (0.50) | ELANEALDH1A1KMT2A | |
| SCHEMBL3223372 | 0.75 | BID (0.50) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL7713405 | 0.74 | BID (0.49) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL9256709 | 0.74 | BID (0.56) | ALDH1A1KDM4EHPGDMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644722-A1 | OPTIMIZED DETERMINATION OF VOLTAGE CHANGES USING A VOLTAGE-SENSITIVE DYE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005001448-A1 | OPTIMIZED DETERMINATION OF VOLTAGE CHANGES USING A VOLTAGE-SENSITIVE DYE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-01-06 | — | — | WO | disclosed |