Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027676 | 0.85 | ELANE (0.46) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5535163 | 0.83 | PTPN1 (0.47) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL2892213 | 0.83 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL2714269 | 0.81 | KDM4E (0.53) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL12425988 | 0.79 | KMT2A (0.38) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL14322033 | 0.77 | TP53 (0.42) | MEN1KMT2AALDH1A1GLANPC1 | |
| SCHEMBL7170202 | 0.76 | WDR5 (0.53) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL897607 | 0.76 | KDM4E (0.55) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10904256 | 0.76 | PTPN22 (0.48) | KDM4ELDHAMAPT | |
| SCHEMBL13466142 | 0.75 | PLK1 (0.35) | MEN1KMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| WO-2011101599-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY AROMATIC NUCLEOPHILIC SUBSTITUTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | COMT, NAA15, NUDC | MEN1 223/4885KMT2A 650/4885KDM4E 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.