⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30683717 | 0.75 | — | — | |
| SCHEMBL29828757 | 0.75 | — | — | |
| SCHEMBL29467490 | 0.75 | — | — | |
| SCHEMBL12902021 | 0.75 | — | — | |
| SCHEMBL4883086 | 0.75 | — | — | |
| SCHEMBL30927454 | 0.75 | — | — | |
| SCHEMBL1349372 | 0.75 | — | — | |
| SCHEMBL376483 | 0.75 | — | — | |
| SCHEMBL913739 | 0.75 | — | — | |
| SCHEMBL7350230 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4178962-B1 | MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2 | NOVARTIS AG (CH) | 2025-06-11 | — | — | EP | claimed |
| CN-119009136-A | Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-11-22 | — | — | CN | claimed |
| CN-115916786-A | Manufacture of compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-113121457-B | Synthesis process of Favipiravir intermediate 3, 6-dichloro-2-cyanopyrazine | 白银康寓信生物科技有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-113121457-A | Synthesis process of Favipiravir intermediate 3, 6-dichloro-2-cyanopyrazine | 白银康寓信生物科技有限公司 | 2021-07-16 | — | — | CN | claimed |
| US-12441737-B2 | Manufacture of compounds and compositions for inhibiting the activity of SHP2 | NOVARTIS AG (CH) | 2025-10-14 | — | — | US | disclosed |
| EP-4178962-B1 | MANUFACTURE OF COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2 | NOVARTIS AG (CH) | 2025-06-11 | — | — | EP | disclosed |
| US-20250179032-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2025-06-05 | — | — | US | disclosed |
| CN-112867718-B | Manufacture of compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-112839715-B | Process for producing compound for inhibiting SHP2 activity | 诺华股份有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-119009136-A | Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-11-22 | — | — | CN | disclosed |
| CN-119013265-A | GLUT9 heterocyclic inhibitors for the treatment of disease | 爱尔兰好利恩治疗有限公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-1341888-B1 | LAUNDRY COMPOSITION | UNILEVER PLC (GB) | 2004-09-22 | — | — | EP | disclosed |
| EP-1341888-A1 | LAUNDRY COMPOSITION | UNILEVER PLC (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-20020155979-A1 | Laundry composition | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-10-24 | — | — | US | disclosed |
| WO-2002048302-A1 | LAUNDRY COMPOSITION | UNILEVER PLC (GB) | 2002-06-20 | — | — | WO | disclosed |
| EP-0915885-A1 | PYRAZINE DERIVATIVES AND THEIR USE FOR MATERIAL AND PLANT PROTECTION | BAYER AG (DE) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004562-A1 | PYRAZINE DERIVATIVES AND THEIR USE FOR MATERIAL AND PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-05 | — | — | WO | disclosed |
| US-4372328-A | Fibrous material for tobacco smoke filter | B.A.T. CIGARETTEN-FABRIKEN GMBH (DE) | 1983-02-08 | — | — | US | disclosed |
| US-4299962-A | Process for synthesizing 2-sulphanilamido-3-methoxypyrazine | PIERREL S.P.A. (IT) | 1981-11-10 | — | — | US | disclosed |