Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028386 | 0.87 | F10 (0.35) | SLC1A2 | |
| SCHEMBL6028353 | 0.86 | P2RX7 (0.33) | ENPP2 | |
| SCHEMBL6028345 | 0.82 | NAMPT (0.33) | FNTAFNTB | |
| SCHEMBL6028373 | 0.81 | F10 (0.36) | SLC1A2 | |
| SCHEMBL6028546 | 0.80 | F10 (0.33) | ENPP2 | |
| Acetic Acid SCHEMBL6029622 | 0.79 | F10 (0.35) | SLC1A2 | |
| SCHEMBL6078168 | 0.78 | SLC1A2 (0.35) | SLC1A2GPR6ENPP2TDP1 | |
| SCHEMBL6078161 | 0.78 | SLC1A2 (0.35) | SLC1A2GPR6ENPP2TDP1 | |
| SCHEMBL6029784 | 0.76 | SLC1A2 (0.37) | SLC1A2GPR6FNTAFNTB | |
| SCHEMBL6029778 | 0.76 | SLC1A2 (0.37) | SLC1A2GPR6FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706396-A1 | N-(4-CARBAMIMIDOYL-BENZYL)-2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA | F.HOFFMANN-LA ROCHE AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005058868-A1 | N-(4-CARBAMIMIDOYL-BENZYL) -2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-30 | — | — | WO | disclosed |