Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028546 | 0.87 | F10 (0.33) | ENPP2 | |
| SCHEMBL6028074 | 0.86 | SLC1A2 (0.34) | ENPP2 | |
| SCHEMBL6028367 | 0.75 | ST14 (0.39) | — | |
| Acetic Acid SCHEMBL6027976 | 0.73 | F10 (0.43) | — | |
| SCHEMBL6028623 | 0.73 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL6078343 | 0.73 | SDCBP (0.34) | P2RX7SETDB1DRD2DRD3DRD4 | |
| SCHEMBL6078352 | 0.73 | SDCBP (0.34) | P2RX7SETDB1DRD2DRD3DRD4 | |
| SCHEMBL6079105 | 0.70 | LMNA (0.40) | DRD2DRD3DRD4 | |
| SCHEMBL6079096 | 0.70 | LMNA (0.40) | DRD2DRD3DRD4 | |
| SCHEMBL6029054 | 0.69 | F10 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706396-A1 | N-(4-CARBAMIMIDOYL-BENZYL)-2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA | F.HOFFMANN-LA ROCHE AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005058868-A1 | N-(4-CARBAMIMIDOYL-BENZYL) -2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-30 | — | — | WO | disclosed |