Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370279 | 0.74 | KDM4E (0.44) | CHRM2KDM4E | |
| SCHEMBL28465259 | 0.72 | KDM4E (0.42) | CHRM2KDM4E | |
| SCHEMBL29907676 | 0.70 | AOC1 (0.43) | BACE1POLBKDM4E | |
| SCHEMBL21722629 | 0.70 | AOC1 (0.43) | BACE1POLBKDM4E | |
| SCHEMBL11623989 | 0.67 | IDO1 (0.45) | BACE1POLBKDM4E | |
| SCHEMBL11983162 | 0.66 | KCNN4 (0.41) | KDM4ESMN1; SMN2 | |
| SCHEMBL7348432 | 0.65 | GAA (0.43) | KDM4ESMN1; SMN2 | |
| SCHEMBL22075675 | 0.64 | METAP1 (0.52) | POLB | |
| SCHEMBL29919353 | 0.64 | METAP1 (0.52) | POLB | |
| SCHEMBL4475474 | 0.63 | PLAU (0.47) | TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638969-A2 | CGRP RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004092166-A2 | CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2004-10-28 | — | — | WO | disclosed |