Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028856 | 0.91 | TLR4 (0.32) | TLR4 | |
| SCHEMBL6029267 | 0.78 | ST14 (0.38) | — | |
| SCHEMBL6028754 | 0.63 | — | — | |
| SCHEMBL6029302 | 0.57 | ALDH1A1 (0.48) | — | |
| SCHEMBL7573680 | 0.57 | LMNA (0.30) | — | |
| SCHEMBL27461888 | 0.56 | ALDH1A1 (0.40) | — | |
| SCHEMBL27360345 | 0.54 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL7953553 | 0.54 | ALDH1A1 (0.37) | — | |
| SCHEMBL10617212 | 0.53 | ALDH1A1 (0.39) | — | |
| SCHEMBL29155813 | 0.53 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706396-A1 | N-(4-CARBAMIMIDOYL-BENZYL)-2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA | F.HOFFMANN-LA ROCHE AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005058868-A1 | N-(4-CARBAMIMIDOYL-BENZYL) -2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-30 | — | — | WO | disclosed |