SCHEMBL6028254

SCHEMBL6028254

CCNc1cc(C(=N)N)ccc1CNC(=O)C(OCC)N1C=C2C=C(Cl)CC(=O)C2C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.33
F2 P00734 1/20 0.31
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6028862 0.90 F10 (0.35) F10F2F7
SCHEMBL6032377 0.82 F10 (0.33) F10
SCHEMBL6029267 0.77 ST14 (0.38) F10F2F7
Acetic Acid SCHEMBL6028236 0.76 F2 (0.39) F10F2F7
SCHEMBL6029054 0.75 F10 (0.35) F10
Acetic Acid SCHEMBL6028580 0.73 F10 (0.34) F10
SCHEMBL6078271 0.73 SDCBP (0.33) F10F2F7F3
SCHEMBL6078241 0.73 SDCBP (0.33) F10F2F7F3
Acetic Acid SCHEMBL6032192 0.72 F10 (0.35) F10F2F7
SCHEMBL6079218 0.71 F10 (0.34) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1706396-A1 N-(4-CARBAMIMIDOYL-BENZYL)-2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA F.HOFFMANN-LA ROCHE AG (CH) 2006-10-04 EP disclosed
WO-2005058868-A1 N-(4-CARBAMIMIDOYL-BENZYL) -2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA F. HOFFMANN-LA ROCHE AG (CH) 2005-06-30 WO disclosed