SCHEMBL6032377

SCHEMBL6032377

CCNc1cc(C(=N)N)ccc1CNC(=O)C(OCC)N1C=C2C=CC(OC)C(=O)C2C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL6029259 0.85 F10 (0.43) F10
SCHEMBL6032824 0.85 F10 (0.39) F10
SCHEMBL6028254 0.82 F10 (0.33) F10
SCHEMBL6028195 0.77 ST14 (0.38) F10
SCHEMBL6029054 0.74 F10 (0.35) F10
SCHEMBL6028490 0.73 ENPP2 (0.33)
SCHEMBL6028862 0.73 F10 (0.35) F10
SCHEMBL6028754 0.73
Acetic Acid SCHEMBL6028580 0.72 F10 (0.34) F10
SCHEMBL6079218 0.71 F10 (0.34) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1706396-A1 N-(4-CARBAMIMIDOYL-BENZYL)-2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA F.HOFFMANN-LA ROCHE AG (CH) 2006-10-04 EP disclosed
WO-2005058868-A1 N-(4-CARBAMIMIDOYL-BENZYL) -2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA F. HOFFMANN-LA ROCHE AG (CH) 2005-06-30 WO disclosed