Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2700564 | 0.81 | TDP1 (0.42) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL2053108 | 0.72 | L3MBTL1 (0.45) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL2465434 | 0.72 | SMN1; SMN2 (0.50) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL6795553 | 0.68 | SMN1; SMN2 (0.50) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL476472 | 0.66 | SMN1; SMN2 (0.43) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL28637349 | 0.65 | L3MBTL1 (0.50) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL8283520 | 0.65 | MAPT (0.52) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL28841329 | 0.65 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2L3MBTL1KDM4EHTT | |
| Urea SCHEMBL28161295 | 0.65 | SMN1; SMN2 (0.54) | TDP1SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL21246245 | 0.64 | SMN1; SMN2 (0.44) | TDP1SLC22A2SLC22A1PGRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694648-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | Bayer CropScience S.A. (FR) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058828-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE S.A. (FR) | 2005-06-30 | — | — | WO | disclosed |