SCHEMBL6028571

SCHEMBL6028571

[CH2]C(C)C[CH]c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.44
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
CYP2A6 P11509 1/20 0.39
NPC1 O15118 1/20 0.33
MTOR P42345 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAOB P27338 1/20 0.33
AHR P35869 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA7 P36544 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543436 0.81 HTR2A (0.47) HTR2AALDH1A1TSHRCYP2A6NPC1
SCHEMBL8826291 0.78 HTR2A (0.66) HTR2AMAOBCHRNB2TDP1
SCHEMBL17004006 0.78 HTR2A (0.41) HTR2AALDH1A1TSHRCYP2A6NPC1
SCHEMBL4351016 0.77 HTR2A (0.64) HTR2ACYP2A6CYP2D6MAOBMAOA
SCHEMBL8105153 0.77 ALDH1A1 (0.39) HTR2AALDH1A1TSHRCYP2A6MTOR
SCHEMBL17330729 0.77 HTR2A (0.44) HTR2AALDH1A1TSHRCYP2A6CYP3A4
SCHEMBL14910878 0.76 TAAR1 (0.50) HTR2ATAAR1
SCHEMBL8166743 0.76 HTR2A (0.42) HTR2AALDH1A1TSHRCYP2A6NPC1
SCHEMBL555307 0.74 HTR2A (0.41) HTR2AMAOBSLC6A2SLC6A4SLC6A3
SCHEMBL28607954 0.74 HTR2A (0.41) HTR2AALDH1A1TSHRCYP2A6NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6989036-B2 Reactive dyes and use thereof for dyeing substrates containing nucleophilic groups BASF AKTIENGELLSCHAFT (DE) 2006-01-24 US disclosed
US-20040102616-A1 Novel reactive dyes and use thereof for dyeing substrates containing nucleophilic groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-27 US disclosed
EP-1392777-A1 NOVEL REACTIVE DYES AND USE THEREOF FOR DYEING SUBSTRATES CONTAINING NUCLEOPHILIC GROUPS BASF AKTIENGESELLSCHAFT (DE) 2004-03-03 EP disclosed
WO-2002088257-A1 NOVEL REACTIVE DYES AND USE THEREOF FOR DYEING SUBSTRATES CONTAINING NUCLEOPHILIC GROUPS BASF AKTIENGESELLSCHAFT (DE) 2002-11-07 WO disclosed
EP-0885897-B1 Optically active diphosphine ligands BASF AG (DE) 2002-08-21 EP disclosed
EP-0906324-B1 CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS BASF AG (DE) 2001-08-01 EP disclosed
EP-0885897-A1 Optically active diphosphine ligands BASF AKTIENGESELLSCHAFT (DE) 1998-12-23 EP disclosed