SCHEMBL6028798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6029791	0.92	MAPK14 (0.49)	MAPK1ROCK2ROCK1RPS6KA5MAP4K4
	SCHEMBL6029303	0.89	ROCK2 (0.48)	MAPK1ROCK2ROCK1RPS6KA5MAP4K4
	SCHEMBL4336706	0.89	MAPK14 (0.43)	ROCK2ROCK1GSK3BMAPK14ALDH1A1
	SCHEMBL6028765	0.88	MAPK14 (0.55)	MAPK1ROCK2ROCK1RPS6KA5MAP4K4
	SCHEMBL4340891	0.87	MAPK14 (0.44)	ROCK2ROCK1GSK3BMAPK14ALDH1A1
	SCHEMBL6029490	0.87	SMN1; SMN2 (0.47)	MAPK1MAPK14ALDH1A1MAPTLMNA
	SCHEMBL6028617	0.85	MAPK1 (0.48)	MAPK1ROCK2ROCK1RPS6KA5MAP4K4
	SCHEMBL6028485	0.82	L3MBTL1 (0.53)	ROCK2ROCK1MAPK14ALDH1A1L3MBTL1
	SCHEMBL6029537	0.82	MAPK14 (0.42)	ROCK2ROCK1GSK3BMAPK14ALDH1A1
	SCHEMBL4340894	0.81	MAPK14 (0.46)	GSK3BMAPK14SRCBRAFKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.