Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250113 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL29833600 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL29833599 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL828619 | 0.81 | KMT2A (0.57) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL11882632 | 0.81 | KMT2A (0.57) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL5469156 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| Methane SCHEMBL8371468 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| Bromide SCHEMBL7400039 | 0.79 | KMT2A (0.55) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL7611308 | 0.79 | KMT2A (0.55) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| Hydrochloric Acid SCHEMBL738023 | 0.79 | KMT2A (0.55) | SMN1; SMN2LMNASTAT6KMT2AASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709040-A2 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF SRC FAMILY PROTEIN KINASE | Sirenade Pharmaceuticals AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005068458-A2 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF SRC FAMILY PROTEIN KINASE | SIRENADE PHARMACEUTICALS AG (DE) | 2005-07-28 | — | — | WO | disclosed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |