Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | STAT6 | P42226 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833599 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL29833600 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL6028992 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL24332893 | 0.83 | DGAT1 (0.51) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| S-Methyl Benzimidazolyldithiocarbamate SCHEMBL27314441 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL11443588 | 0.79 | KMT2A (0.60) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL10979942 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL250172 | 0.79 | HTT (0.66) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL857765 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL3078847 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNASTAT6KMT2AASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303799-A1 | PROCESS FOR THE PREPARATION OF POLY(ALKYLENE OXIDE) DERIVATIVES FOR MODIFICATION OF BIOLOGICALLY ACTIVE MOLECULES AND MATERIALS | HORIAN AMERICA, CORP. | 2013-11-14 | — | — | US | disclosed |
| WO-2012003045-A2 | PROCESS FOR THE PREPARATION OF POLY(ALKYLENE OXIDE) DERIVATIVES FOR MODIFICATION OF BIOLOGICALLY ACTIVE MOLECULES AND MATERIALS | HORIAN AMERICA, CORP. (US) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303799-A1 | PROCESS FOR THE PREPARATION OF POLY(ALKYLENE OXIDE) DERIVATIVES FOR MODIFICATION OF BIOLOGICALLY ACTIVE MOLECULES AND MATERIALS | PBRM1, PAM, PARG | SMN1; SMN2 2461/4885LMNA 11/4885STAT6 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.