Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.59 |
| ▸ | PI4KA | P42356 | 2/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.55 |
| ▸ | AHCY | P23526 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029352 | 0.87 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL6029039 | 0.80 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL9204975 | 0.80 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL4811419 | 0.79 | ADORA2A (0.72) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL7134825 | 0.79 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| Hydrochloric Acid SCHEMBL10339774 | 0.78 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL6029347 | 0.78 | ADCY5 (0.65) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL11222112 | 0.78 | ADORA2A (0.80) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL14355770 | 0.78 | ADCY5 (0.57) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL5810639 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478653-B1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| CN-101289483-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2012-06-20 | — | — | CN | disclosed |
| CN-101367854-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2010-12-29 | — | — | CN | disclosed |
| CN-100509833-C | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-07-08 | — | — | CN | disclosed |
| CN-101367854-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-02-18 | — | — | CN | disclosed |
| CN-101289483-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| CN-101289484-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| US-6995143-B2 | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-02-07 | — | — | US | disclosed |
| CN-1630661-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2005-06-22 | — | — | CN | disclosed |
| EP-1478653-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | Basilea Pharmaceutica AG (CH) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072588-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2003-09-04 | — | — | WO | disclosed |