Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.69 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | PI4KA | P42356 | 2/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.56 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.55 |
| ▸ | AHCY | P23526 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029347 | 0.88 | ADCY5 (0.65) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL13870063 | 0.84 | ADCY5 (0.61) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL29459142 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL984944 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL14355770 | 0.81 | ADCY5 (0.57) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL11610452 | 0.81 | AHCY (0.67) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| Hydrochloric Acid SCHEMBL9193028 | 0.81 | ADORA2A (0.97) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL9204975 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL4811419 | 0.80 | ADORA2A (0.72) | ADORA2AADORA1ADCY5ADORA2BPI4KA | |
| SCHEMBL6029046 | 0.80 | ADORA2A (0.63) | ADORA2AADORA1ADCY5ADORA2BPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2255683-A | — | — | None | — | — | JP | disclosed |
| JP-3232806-A | — | — | None | — | — | JP | disclosed |
| EP-1478653-B1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| CN-101289483-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2012-06-20 | — | — | CN | disclosed |
| CN-101367854-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2010-12-29 | — | — | CN | disclosed |
| CN-100509833-C | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-07-08 | — | — | CN | disclosed |
| CN-101367854-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-02-18 | — | — | CN | disclosed |
| CN-101289483-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| CN-101289484-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| US-6995143-B2 | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-02-07 | — | — | US | disclosed |
| CN-1630661-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2005-06-22 | — | — | CN | disclosed |
| EP-1478653-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | Basilea Pharmaceutica AG (CH) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072588-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2003-09-04 | — | — | WO | disclosed |
| JP-H03232806-A | CROP YIELD INCREASING AGENT | MITSUBISHI GAS CHEM CO INC | 1991-10-16 | — | — | JP | disclosed |
| JP-H02255683-A | ADENINE DERIVATIVE | MITSUBISHI GAS CHEM CO INC | 1990-10-16 | — | — | JP | disclosed |