Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ME2 | P23368 | 1/20 | 0.51 |
| ▸ | ME1 | P48163 | 1/20 | 0.51 |
| ▸ | ME3 | Q16798 | 1/20 | 0.51 |
| ▸ | GHSR | Q92847 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702559 | 0.89 | KMT2A (0.68) | MEN1KMT2AUSP2GAAPOLB | |
| SCHEMBL6031895 | 0.85 | MEN1 (0.58) | MEN1KMT2AUSP2GAAPOLB | |
| SCHEMBL18068774 | 0.82 | OPRM1 (0.62) | MEN1KMT2ALMNACA12CA1 | |
| SCHEMBL2702458 | 0.81 | KMT2A (0.62) | MEN1KMT2AGAAPOLBRCE1 | |
| SCHEMBL2471715 | 0.81 | ALDH1A1 (0.57) | MEN1KMT2AUSP2GAAPOLB | |
| SCHEMBL10721826 | 0.80 | MEN1 (1.00) | MEN1KMT2AUSP2GAAPOLB | |
| SCHEMBL6032506 | 0.80 | CA12 (0.55) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL6031458 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AGAAPOLBRCE1 | |
| SCHEMBL6032504 | 0.78 | CA12 (0.54) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL2636624 | 0.78 | CA12 (0.59) | MEN1KMT2AALDH1A1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058351-A1 | Novel ligands that modulate LXR-type receptors and cosmetic/pharmaceutical applications thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-03-16 | — | — | US | claimed |
| EP-1599447-A1 | LIGANDS THAT MODULATE LXR-TYPE RECEPTORS | Galderma Research & Development, S.N.C. (FR) | 2005-11-30 | — | — | EP | claimed |
| WO-2004076418-A1 | LIGANDS THAT MODULATE LXR-TYPE RECEPTORS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-09-10 | — | — | WO | claimed |
| US-20060058351-A1 | Novel ligands that modulate LXR-type receptors and cosmetic/pharmaceutical applications thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-03-16 | — | — | US | disclosed |
| EP-1599447-A1 | LIGANDS THAT MODULATE LXR-TYPE RECEPTORS | Galderma Research & Development, S.N.C. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076418-A1 | LIGANDS THAT MODULATE LXR-TYPE RECEPTORS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058351-A1 | Novel ligands that modulate LXR-type receptors and cosmetic/pharmaceutical applications thereof | NR1H2, NR1H3, RXRG | MEN1 4039/4885KMT2A 2050/4885USP2 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.