Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.59 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072596 | 0.84 | MAPK14 (0.82) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL5456029 | 0.79 | MAPK14 (0.78) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL5216405 | 0.79 | MAPK14 (0.57) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL3423125 | 0.78 | MAPK14 (0.43) | MAPK14MAPK11 | |
| SCHEMBL3225734 | 0.78 | MAPK14 (0.44) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL6031999 | 0.78 | MAPK14 (0.59) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL5122607 | 0.78 | MAPK14 (0.60) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL5216080 | 0.77 | MAPK14 (0.88) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL4861254 | 0.77 | MAPK14 (0.67) | MAPK14MAP2K1MAPK11 | |
| SCHEMBL4865916 | 0.77 | MAPK14 (0.67) | MAPK14MAP2K1MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687284-A2 | p-38 KINASE INHIBITORS | Novartis AG (CH) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005012241-A2 | p-38 KINASE INHIBITORS | NOVARTIS AG (CH) | 2005-02-10 | — | — | WO | disclosed |