Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.49 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28695915 | 0.91 | CES2 (0.59) | FAAHCES1CES2MAPTCYP1A2 | |
| Trifluoroacetic Acid SCHEMBL28695896 | 0.91 | CES2 (0.59) | FAAHCES1CES2MAPTCYP1A2 | |
| Laurixamine SCHEMBL28679807 | 0.91 | CES2 (0.59) | FAAHCES1CES2MAPTCYP1A2 | |
| Trifluoroacetic Acid SCHEMBL9116974 | 0.91 | CES2 (0.59) | FAAHCES1CES2MAPTCYP1A2 | |
| SCHEMBL1980993 | 0.84 | LPAR1 (0.49) | FAAH | |
| SCHEMBL4177958 | 0.84 | LPAR1 (0.49) | FAAH | |
| SCHEMBL4177952 | 0.84 | LPAR1 (0.49) | FAAH | |
| SCHEMBL1980991 | 0.84 | LPAR1 (0.49) | FAAH | |
| Hydrochloric Acid SCHEMBL28863390 | 0.83 | DNM1 (0.48) | — | |
| Bromide SCHEMBL28661101 | 0.83 | DNM1 (0.48) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573017-B | Mesenchymal stromal cells for the treatment of sepsis | 泰根尼克斯独资有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-7070807-B2 | Branched histidine copolymers and methods for using same | MIXSON A JAMES | 2006-07-04 | — | — | US | disclosed |