Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | FABP2 | P12104 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425494 | 0.96 | SRD5A2 (0.67) | SRD5A2HPGDMEN1NPC1CASP3 | |
| SCHEMBL822861 | 0.92 | HPGD (0.70) | SRD5A2HPGDPARP10RAB9AKMT2A | |
| SCHEMBL822832 | 0.92 | HPGD (0.70) | SRD5A2HPGDPARP10RAB9AKMT2A | |
| SCHEMBL12861795 | 0.92 | HPGD (0.70) | SRD5A2HPGDPARP10RAB9AKMT2A | |
| SCHEMBL23559522 | 0.92 | SRD5A2 (0.62) | SRD5A2HPGDPARP10MEN1NPC1 | |
| SCHEMBL9452119 | 0.91 | SRD5A2 (0.61) | SRD5A2HPGDMEN1NPC1CASP3 | |
| SCHEMBL1082112 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10ALDH1A1POLB | |
| SCHEMBL9536469 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10ALDH1A1POLB | |
| SCHEMBL235530 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10ALDH1A1POLB | |
| SCHEMBL2866068 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652833-A1 | PROCESS FOR PRODUCING 4-HYDROXYDIPHENYL ETHER | Sumitomo Chemical Company, Limited (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-0455332-B1 | Acylation or sulphonylation of aromatic compounds | ZENECA LTD (GB) | 1996-02-21 | — | — | EP | disclosed |
| US-5256826-A | Catalytically reacting phenols with halogenated carboxyl or sulfonyl aromatic compounds | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| EP-0532965-A2 | Process for the preparation of aromatic carbonyl- or sulfonyl compounds with aryletherstructure | BASF Aktiengesellschaft (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5164527-A | Zeolite catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-17 | — | — | US | disclosed |
| EP-0455332-A2 | Acylation or sulphonylation of aromatic compounds | ZENECA LIMITED (GB) | 1991-11-06 | — | — | EP | disclosed |
| US-4226783-A | OF SIDE CHAINS OF ELECTRONEGATIVELY SUBSTITUTED AROMATIC COMPOUNDS WITH DICHLORINE MONOXIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |