Sugi Predict

Sugi Predict / Compounds / SCHEMBL822832

SCHEMBL822832

SCHEMBL822832

O=C(c1ccc(Cl)cc1)c1ccc(Oc2ccc(C(=O)c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.70
▸ SRD5A2 P31213 2/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ ELANE P08246 1/20 0.59
▸ FABP2 P12104 1/20 0.58
▸ PPARG P37231 1/20 0.58
▸ PPARA Q07869 1/20 0.58
▸ SLC22A12 Q96S37 1/20 0.58
▸ MMP1 P03956 2/20 0.54
▸ CES2 O00748 1/20 0.52
▸ CES1 P23141 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ PARP15 Q460N3 1/20 0.52
▸ PARP14 Q460N5 1/20 0.52
▸ PARP10 Q53GL7 1/20 0.52
▸ PARP16 Q8N5Y8 1/20 0.52
▸ PARP11 Q9NR21 1/20 0.52
▸ PARP4 Q9UKK3 1/20 0.52
▸ MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822861 1.00 HPGD (0.70) HPGDSRD5A2MAPK1ELANEFABP2
SCHEMBL12861795 1.00 HPGD (0.70) HPGDSRD5A2MAPK1ELANEFABP2
SCHEMBL822863 0.94 HPGD (0.63) HPGDSRD5A2MAPK1ELANEFABP2
SCHEMBL9507303 0.92 MAPK1 (0.77) HPGDSRD5A2MAPK1ELANEFABP2
SCHEMBL6032445 0.92 SRD5A2 (0.72) HPGDSRD5A2MAPK1FABP2PPARG
SCHEMBL8967203 0.92 MAPK1 (0.77) HPGDSRD5A2MAPK1ELANEFABP2
SCHEMBL6425494 0.92 SRD5A2 (0.67) HPGDSRD5A2ELANEFABP2PPARG
SCHEMBL9506642 0.92 MAPK1 (0.77) HPGDSRD5A2MAPK1ELANEFABP2
SCHEMBL9777083 0.90 HPGD (0.59) HPGDSRD5A2MAPK1ELANEFABP2
SCHEMBL822835 0.90 HPGD (0.59) HPGDSRD5A2MAPK1ELANEFABP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 — — EP claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 — — US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 — — EP claimed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 — — US disclosed
US-8236920-B2 Polyarylene and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 — — US disclosed
EP-1693405-B1 PROTON CONDUCTING MEMBRANE AND PROCESS FOR PRODUCING THE SAME JSR CORP (JP) 2012-05-02 — — EP disclosed
US-8088883-B2 Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-03 — — US disclosed
US-8058365-B2 Proton conducting membrane and process for producing the same JSR CORPORATION (JP) 2011-11-15 — — US disclosed
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2011-11-10 — — US disclosed
US-20110275780-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMCIAL COMPANY LIMITED 2011-11-10 — — US disclosed
US-8039165-B2 Proton conductive membrane comprising a copolymer JSR CORPORATION (JP) 2011-10-18 — — US disclosed
EP-0178184-A1 Preparation of aromatic carbonyl compounds RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 — — EP disclosed
US-4567248-A Branched, high molecular weight, thermoplastic polyarylene ethers containing nitrile groups, and their preparation BASF AKTIENGESELLSCHAFT (DE) 1986-01-28 — — US disclosed
EP-0147708-A2 Polyaryl ethers containing branched, high molecular weight thermoplastic nitrile groups, and their preparation BASF Aktiengesellschaft (DE) 1985-07-10 — — EP disclosed
EP-0135130-A2 Process for the preparation of polyethers BASF Aktiengesellschaft (DE) 1985-03-27 — — EP disclosed
US-4324881-A FROM DIHALOBENZENE COMPOUND AND AMIDE-CONTAINING BISPHENOL, ALKALI METAL CARBONATE BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 — — US disclosed
US-4324881-A FROM DIHALOBENZENE COMPOUND AND AMIDE-CONTAINING BISPHENOL, ALKALI METAL CARBONATE BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 — — US disclosed
US-4200728-A Manufacture of polyethers from bis-(4-hydroxyphenyl)-sulfone and bis-(4-chlorophenyl)-sulfone in N-methylpyrrolidone using an alkali metal carbonate as catalysts BASF AKTIENGESELLSCHAFT (DE) 1980-04-29 — — US disclosed
US-4200727-A Manufacture of polyethers from bisphenols and dihalides in the absence of solvent and in the presence of alkali metal carbonate BASF AKTIENGESELLSCHAFT (DE) 1980-04-29 — — US disclosed
US-4065437-A Aromatic polyether-sulfones BASF AKTIENGESELLSCHAFT (DT) 1977-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND C9, H1-10, CYP1A1 HPGD 3914/4885SRD5A2 3817/4885MAPK1 1740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.