Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.49 |
| ▸ | CD74 | P04233 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728620 | 0.92 | ROCK2 (0.58) | ROCK2 | |
| SCHEMBL2728616 | 0.92 | ROCK2 (0.58) | ROCK2 | |
| SCHEMBL6031918 | 0.89 | ROCK2 (0.53) | ROCK2 | |
| SCHEMBL6032831 | 0.89 | ROCK2 (0.51) | ROCK2 | |
| SCHEMBL6032908 | 0.86 | ROCK2 (0.49) | ROCK2 | |
| SCHEMBL6031649 | 0.86 | ROCK2 (0.50) | ROCK2 | |
| SCHEMBL2725268 | 0.86 | ROCK2 (0.66) | ROCK2 | |
| SCHEMBL2728359 | 0.86 | ROCK2 (0.66) | ROCK2 | |
| SCHEMBL2725266 | 0.86 | ROCK2 (0.66) | ROCK2 | |
| SCHEMBL6030813 | 0.85 | ROCK2 (0.54) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054367-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |