Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032831 | 0.92 | ROCK2 (0.51) | ROCK2 | |
| SCHEMBL2727428 | 0.92 | ROCK2 (0.55) | ROCK2 | |
| SCHEMBL2727424 | 0.92 | ROCK2 (0.55) | ROCK2 | |
| SCHEMBL6031649 | 0.91 | ROCK2 (0.50) | ROCK2 | |
| SCHEMBL6032780 | 0.90 | ROCK2 (0.52) | ROCK2 | |
| SCHEMBL6031918 | 0.89 | ROCK2 (0.53) | ROCK2 | |
| SCHEMBL6032480 | 0.86 | ROCK2 (0.49) | ROCK2 | |
| SCHEMBL2728169 | 0.85 | ROCK2 (0.54) | ROCK2 | |
| SCHEMBL2728167 | 0.85 | ROCK2 (0.54) | ROCK2 | |
| SCHEMBL2728724 | 0.83 | ROCK2 (0.57) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054367-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |